Undergraduate Research in Medical Engineering
Variable units as arranged with the advising faculty member | first, second, third terms
Undergraduate research with a written report at the end of each term; supervised by a Caltech faculty member, or co-advised by a Caltech faculty member and an external researcher. Graded pass/fail.
MedE 100 abc
Medical Engineering Seminar
1 unit | first, second, third terms
All PhD degree candidates in Medical Engineering are required to attend all MedE seminars. If there is no MedE seminar during a week, then the students should go to any other graduate-level seminar that week. Students should broaden their knowledge of the engineering principles and sciences of medical engineering. Students are expected to learn the forefronts of the research and development of medical materials, technologies, devices and systems from the seminars. Graded pass/fail.
Introduction to Clinical Physiology and Pathophysiology for Engineers
9 units (3-0-6) | First term
Prerequisites: No Prerequisites, Bi 1 or equivalent recommended.
The goal of this course is to introduce engineering scientists to medical physiological systems: with a special emphasis on the clinical relevance. The design of the course is to present two related lectures each week in a case study format: An overview of the physiology of a system followed by examples of pathophysiology as well as diagnostic and therapeutic modalities. The Final two weeks of the course will be a mini-work shop where the class explores challenging problems in medical physiology. The course ultimately seeks to promote a bridge between relevant clinical problems and engineering scientists who desire to solve them. Graded pass/fail.
Introduction to Biomechanics
9 units (3-0-6) | third term
Introduction to the basic concepts of applying engineering principles of solid and fluid mechanics to the study of biological systems. The course emphasizes the organismal, rather than the molecular, level of complexity. It draws on a wide array of biological phenomena from plants and animals, and is not intended as a technical introduction to medically related biomechanics. Topics may include fundamental properties of solids and fluids, viscoelasticity, drag, biological pumps, locomotion, and muscle mechanics. Not offered 2014-15.
EE/MedE 114 ab
Analog Circuit Design
12 units (4-0-8) | second, third terms
Prerequisites: EE 44 or equivalent.
Analysis and design of analog circuits at the transistor level. Emphasis on design-oriented analysis, quantitative performance measures, and practical circuit limitations. Circuit performance evaluated by hand calculations and computer simulations. Recommended for juniors, seniors, and graduate students. Topics include: review of physics of bipolar and MOS transistors, low-frequency behavior of single-stage and multistage amplifiers, current sources, active loads, differential amplifiers, operational amplifiers, high-frequency circuit analysis using time- and transfer constants, high-frequency response of amplifiers, feedback in electronic circuits, stability of feedback amplifiers, and noise in electronic circuits, and supply and temperature independent biasing. A number of the following topics will be covered each year: trans-linear circuits, switched capacitor circuits, data conversion circuits (A/D and D/A), continuous-time Gm.C filters, phase locked loops, oscillators, and modulators. Not Offered 2014-15.
9 units (3-0-6) | first term
Prerequisites: Introductory electromagnetic class and consent of the instructor.
The course will cover various electro-optical phenomena and devices in the micro-/nano-scales. We will discuss basic properties of light, imaging, aberrations, eyes, detectors, lasers, micro-optical components and systems, scalar diffraction theory, interference/interferometers, holography, dielectric/plasmonic waveguides, and various Raman techniques. Topics may vary. Not offered 2014-15.
Mixed-mode Integrated Circuits
9 units (3-0-6) | third term
Prerequisites: EE 45 a or equivalent.
Introduction to selected topics in mixed-signal circuits and systems in highly scaled CMOS technologies. Design challenges and limitations in current and future technologies will be discussed through topics such as clocking (PLLs and DLLs), clock distribution networks, sampling circuits, high-speed transceivers, timing recovery techniques, equalization, monitor circuits, power delivery, and converters (A/D and D/A). A design project is an integral part of the course.
Optical Methods for Biomedical Imaging and Diagnosis
9 units (3-1-5) | third term
Prerequisites: EE 151 or equivalent.
Topics include Fourier optics, scattering theories, shot noise limit, energy transitions associated with fluorescence, phosphorescence, and Raman emissions. Study of coherent anti-Stokes Raman spectroscopy (CARS), second harmonic generation and near-field excitation. Scattering, absorption, fluorescence, and other optical properties of biological tissues and the changes in these properties during cancer progression, burn injury, etc. Specific optical technologies employed for biomedical research and clinical applications: optical coherence tomography, Raman spectroscopy, photon migration, acousto-optics (and opto-acoustics) imaging, two-photon fluorescence microscopy, and second- and third-harmonic microscopy. Given in alternate years; offered 2014-15.
MEMS Technology and Devices
9 units (3-0-6) | third term
Prerequisites: APh/EE 9 ab, or instructor's permission.
Micro-electro-mechanical systems (MEMS) have been broadly used for biochemical, medical, RF, and lab-on-a-chip applications. This course will cover both MEMS technologies (e.g., micro- and nanofabrication) and devices. For example, MEMS technologies include anisotropic wet etching, RIE, deep RIE, micro/nano molding and advanced packaging. This course will also cover various MEMS devices used in microsensors and actuators. Examples will include pressure sensors, accelerometers, gyros, FR filters, digital mirrors, microfluidics, micro total-analysis system, biomedical implants, etc. Not offered 2014-15.
VLSI and ULSI Technology
9 units (3-0-6) | third term
Prerequisites: APh/EE 9 ab, EE/APh 180 or instructor's permission.
This course is designed to cover the state-of-the-art micro/nanotechnologies for the fabrication of ULSI including BJT, CMOS, and BiCMOS. Technologies include lithography, diffusion, ion implantation, oxidation, plasma deposition and etching, etc. Topics also include the use of chemistry, thermal dynamics, mechanics, and physics. Not offered 2014-15.
BE/EE/MedE 189 ab
Design and Construction of Biodevices
12 units (3-6-3 a); 9 units (0-9-0 b) | a = third term; b = first term
Prerequisites: ACM 95 ab (for BE/EE/MedE 189 a); BE/EE/MedE 189 a (for BE/EE/MedE 189 b).
Part a, students will design and implement biosensing systems, including a pulse monitor, a pulse oximeter, and a real-time polymerase-chain-reaction incubator. Students will learn to program in LABVIEW. Part b is a student-initiated design project requiring instructor's permission for enrollment. Enrollment is limited to 24 students. BE/EE/MedE 189 a is an option requirement; BE/EE/MedE 189 b is not.
Special Topics in Medical Engineering
Units to be arranged, terms to be arranged
Subject matter will change from term to term depending upon staff and student interest, but will generally center on the understanding and applying engineering for medical problems.
MedE 201 ab
Principles and Design of Medical Devices
9 units (3-0-6) | second and third term
Prerequisites: instructor's permission.
This course provides a broad coverage on the frontiers of medical diagnostic and therapeutic technologies and devices based on multidisciplinary engineering principles. Topics include biomaterials and biomechanics; micro/nanofluidics; micro/nano biophotonics and medical imaging; medical electronics, wireless communications through the skin and tissue; electrograms and biotic/abiotic interface; biochips, microPCR and sequencer and biosensors; micro/nano implants. The course will focus on the scientific fundamentals specific to medical applications. However, both the lectures and assignments will also emphasize the design aspects of the topics as well as up-to-date literature study.
Instructors: Tai, Choo
Biological Flows: Transport and Circulatory Systems
9 units (3-0-6) | second term
Prerequisites: Ae/APh/CE/ME 101 abc or equivalent or ChE 103 a.
Internal flows: steady and pulsatile blood flow in compliant vessels, internal flows in organisms. Fluid dynamics of the human circulatory system: heart, veins, and arteries (microcirculation). Mass and momentum transport across membranes and endothelial layers. Fluid mechanics of the respiratory system. Renal circulation and circulatory system. Biological pumps.
Research in Medical Engineering
Units to be arranged | first, second, third terms
Qualified graduate students are advised in medical engineering research, with the arrangement of MedE staff.
Published Date: July 28, 2022